These are mostly varieties of "good germs" that live in everybody. But Wednesday's study also hints that the make up of this microbial colony plays a role in premature birth.
what makes up these colonies and calculated that healthy adults cohabitate with more than 10,000 species.
WASHINGTON (AP) Surprising new research shows a small but diverse community of bacteria lives in the placentas of healthy pregnant women, overturning the belief that fetuses grow in a pretty sterile environment.
Aagard's team earlier had studied the microbiome of the vagina, and learned that its composition changes when a woman becomes pregnant. The puzzle: The most common vaginal microbes weren't the same as the earliest gut bacteria that scientists were finding in newborns.
"It allows us to think about the biology of pregnancy in different ways than we have before, that pregnancy and early life aren't supposed to be these totally sterile events," said lead researcher Dr. Kjersti Aagaard of Baylor College of Medicine in Houston.
We share our bodies with trillions of microbes on the skin, in the gut, in the mouth. These communities are called our microbiome, and many bacteria play critical roles in keeping us healthy, especially those in the intestinal tract. A few years ago, the government's Human Microbiome Project mapped Nike Air Max Tavas Womens
With colleagues from Baylor and Texas Children's Hospital, Aagaard analyzed 320 donated placentas, using technology that teases out bacterial DNA to evaluate the type and abundance of different microbes.
In fact, among the 89 placentas that were collected after preterm births, levels of some of the apparently helpful bacteria were markedly lower, she said.
realize that microbes may play a role even in fetus development," added Proctor, who wasn't involved in the work. "The results of this study now open up a whole new line of research on maternal and pediatric health."
Aagaard is beginning a larger study to explore the link, planning to analyze the oral and placental microbiomes of more than 500 pregnant women at risk of preterm birth.
Healthy newborns pick up some from their mother during birth, different bugs depending on whether they were delivered vaginally or by C section.
Bacteria live even in healthy placentas
What about before birth? There have been some signs that the process could begin in utero.
With the new research, "we Nike Thea Tan
But, "we have traditionally believed in medicine Nike Air Max Tavas Size 7
that the uterus is a sterile part of the human body," said Dr. Lita Proctor of the National Institutes of Health, who oversaw the microbiome project.
But to Aagaard's surprise, the placental microbiome most resembled bacteria frequently found in the mouth, she reported in the journal Science Translational Medicine. The theory: Oral microbes slip into the mother's bloodstream and make their way to the placenta.
Why does the body allow them to stay? Aagaard said there appears to be a role for different microbes. Some metabolize nutrients. Some are toxic to yeast and parasites. Some act a bit like natural versions of medications used to stop preterm contractions, she said.
What else, Aagaard wondered, could be "seeding" the infants' intestinal Nike Air Max Tavas Khaki Olive tract?
The placenta isn't teeming with microbes it harbors a low level, Aagaard stressed. Among them are kinds of E. coli that live in the intestines of most healthy people.
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